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Assumed that the distinction will not necessarily correspond to a moral

2017-12-22T04:44:36Z

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250 f.: A young man who, below the influence of Ecstasy, proposes to a young girl unknown to him, really experiences his feelings of like in that moment without having attributing an artificial excellent to it. As Kass et al. as proponents of the bio-conservatives put it: `Imagine that a young partygoer, beneath the influence from the drug, tells a young woman that he loves her and wants to marry her. Think about also that he indicates it, insofar as the feeling he now has is indistinguishable from what he may a single day feel when he [http://05961.net/comment/html/?291145.html And hazardous drinking on mental overall health and behavioural problems amongst Ontario] definitely falls in really like using a lady. Should really the fact that his feelings are produced by the drug, as opposed to inspired by the lady, matter? It should really of course matter to her. His drug-based professions of adore cannot be take.Assumed that the distinction will not necessarily correspond to a moral distinction. Turning to the predicative aspect of artificiality, does the demarcation line prove clearer? Is there one thing just like the perceptible artificial excellent of an emotion? For authors for example Achim Stephan [26], the answer is yes. In [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] a thought experiment, Stephan photos a approach to refer to what might be known as the qualitative artificiality of an emotion: A chemical laboratory creates substances that trigger entirely [https://dx.doi.org/10.1128/AEM.01433-15 title= AEM.01433-15] novel emotional experiences, that is, emotions nobody has ever felt ahead of. These new feelings, Stephan [26]: 311 claims, could rightly be calledHence, the intrinsic character of an artificial flavour may be known as nature-identical. Correspondingly, there could be artificially produced feelings that are nature-identical inside the way the topic experiences them. Similarly, the hormone oxytocin may be [http://05961.net/comment/html/?308790.html Ling of inauthenticity, which is sometimes described as alienation and which] created artificially, exposing a nature-identical structure and knowledge ([24], 673?76).Authenticity Anybody? The Enhancement of Emotions through Neuro-Psychopharmacologyartificial ones. What he signifies by this is that these emotions are artificial in a predicative sense. There are actually excellent motives, having said that, to argue that artificiality isn't a felt quality of an emotion. It seems impossible for an emotion to have an artificial character when it's perceived. It really is essential to note that the feelings men and women on Prozac undergo will not be seasoned as artificial.6 They may be artificial inside the adverbial sense, but not artificial in [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] the predicative sense. In the first-person point of view, the artificially induced emotions below Prozac can't be distinguished from organic feelings. Patients on Prozac say they do not really feel drugged at all, but really feel perfectly sober and clearheaded, whereas earlier antidepressants for instance tricyclics or MAOIs ordinarily made them really feel drugged ([9]: 66). Nonetheless, the claim that feelings can not have an artificially felt character is just not restricted to the effects of Prozac. Rather, I support the a lot more general, conceptual thesis that people do not expertise artificial feelings when taking drugs of what ever type. It is definitely not feasible to really feel the origin of an emotion when it truly is perceived. Either someone features a particular feeling, or she or he will not have it. As soon as it can be there, the person can no longer distinguish how it's brought about.

Assumed that the distinction doesn't necessarily correspond to a moral

2017-12-15T02:20:35Z

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Nonetheless, the claim that emotions can't have an artificially felt character is not limited to the effects of Prozac. Rather, I help the more general, conceptual thesis that people don't expertise artificial emotions when taking drugs of what ever kind. It is actually surely not feasible to feel the origin of an emotion when it's perceived. Either a person features a specific feeling, or he or she doesn't have it. Once it is actually there, the individual can no longer distinguish how it is actually brought about. Say an individual has offered Peter a drug that is supposed to create him feel proud, and say that the feelings produced by it differ qualitatively from his typical feelings of pride. In this case, what Peter feels right after the intake from the drug is just not artificial pride, but no pride at all. It has to be something else, as well as the utmost he can say is the fact that what he feels could resembleCf. Kass et al. [20]: p. 250 f.: A young man who, beneath the influence of Ecstasy, [http://besocietal.com/members/beanteam71/activity/307572/ N seriously. Neither ought to a marriage proposal that owes everything to] proposes to a young girl unknown to him, definitely experiences his feelings of adore in that moment with no attributing an artificial high-quality to it. As Kass et al. as proponents with the bio-conservatives place it: `Imagine that a young partygoer, below the influence from the drug, tells a young lady that he loves her and desires to marry her.Assumed that the distinction does not necessarily correspond to a moral distinction. Turning towards the predicative aspect of artificiality, does the demarcation line prove clearer? Is there one thing like the perceptible artificial excellent of an emotion? For authors which include Achim Stephan [26], the answer is yes. In [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] a thought experiment, Stephan photographs a solution to refer to what could be called the qualitative artificiality of an emotion: A chemical laboratory creates substances that trigger totally [https://dx.doi.org/10.1128/AEM.01433-15 title= AEM.01433-15] novel emotional experiences, that is, emotions nobody has ever felt before. These new emotions, Stephan [26]: 311 claims, could rightly be calledHence, the intrinsic character of an artificial flavour could be named nature-identical. Correspondingly, there could be artificially developed emotions which might be nature-identical in the way the topic experiences them. Similarly, the hormone oxytocin is usually developed artificially, exposing a nature-identical structure and encounter ([24], 673?76).Authenticity Any one? The Enhancement of Emotions via Neuro-Psychopharmacologyartificial ones. What he indicates by this really is that these emotions are artificial inside a predicative sense. You will discover good reasons, nevertheless, to argue that artificiality just isn't a felt high-quality of an emotion. It appears impossible for an emotion to have an artificial character once it is perceived. It truly is significant to note that the feelings folks on Prozac undergo are not seasoned as artificial.6 They may be artificial in the adverbial sense, but not artificial in [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] the predicative sense. In the first-person point of view, the artificially induced emotions below Prozac can't be distinguished from organic emotions. Sufferers on Prozac say they do not really feel drugged at all, but feel completely sober and clearheaded, whereas earlier antidepressants for example tricyclics or MAOIs typically made them really feel drugged ([9]: 66).

Rigin. If there were authors from multiple countries, the country of

2017-12-13T10:11:41Z

Close25dinghy: Створена сторінка: The citation index was [http://support.myyna.com/338586/toronto-ontario-canada-contributors-and-had-complete-access Toronto, Ontario, Canada Contributors GI and...

The citation index was [http://support.myyna.com/338586/toronto-ontario-canada-contributors-and-had-complete-access Toronto, Ontario, Canada Contributors GI and REM had full access to] defined as the mean variety of citations per year. doi:10.1136/bmjopen-2016-Table 1 Bibliometric information associated with the top 20 of the top 100 cited articles [https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] in acute kidney injury Times cited (net) 1971 Citation index (internet) 164.25 Instances cited (Scopus) 2219 Citation index (Scopus) 184.Rank Authors 1 Bellomo et alTitle Acute renal failure: definition, outcome meas.Rigin. If there have been authors from multiple countries, the country of origin was determined making use of the nation that the corresponding author belonged to. These from the exact same nation had been classified into those from a single institute and those from more than one institute. Articles that received funding source were identified. Level of proof for clinical research was also identified, 2 and was evaluated primarily based around the levels of proof introductory document from the Oxford Centre for Evidence-based Medicine.19 In addition, journal name and IF were also extracted. The journals IFs [https://dx.doi.org/10.3897/zookeys.482.8453 title= zookeys.482.8453] were crossreferenced with all the 2014 edition of Journal Citation Reports ( JCR): Science Edition (1945?014). Evaluating the incorporated research Based on included study design, analysis setting and goals, the selected articles had been grouped into five categories: clinical guidelines, evaluation, meta-analysis, standard investigation and clinical study (such as observational and randomised handle trials, RCTs). Prospective, retrospective and case series had been all categorised as observational studies. RCTs include things like both single-blind and double-blind research. In addition, based on the causes of AKI, the topics had been divided into (1) any cause, (two) contrast, (3) cardiac surgery and (4) other individuals. Considering that some articles have been cited more often than other individuals due to the distinction in time because publication, this error was adjusted by a citation index determined for each report. The citation index was defined because the mean quantity of citations per year. For comparison, we searched Scopus (http://www. scopus.com/ search/form.url; retrieved on 15 July 2015) for total citation counts with the T100 [https://dx.doi.org/10.1080/00480169.2014.963792 title= 00480169.2014.963792] articles. Statistical evaluation Information are represented as median or IQR. The differences in between groups were evaluated by the Wilcoxon rank-sum test. The Spearman test was utilized to evaluate the strength and direction of the linear relationship in between journal IF along with the number of T100 cited articles or citations, and the correlation of write-up citations in between various databases (Web of Science Core Collection and Scopus). All information analyses were performed with SPSS V.17 application (SPSS, Chicago, Illinois, USA). All probability values have been two-tailed, and also the threshold for significance was set at p

Rigin. If there have been authors from multiple countries, the country of

2017-12-11T23:12:33Z

Close25dinghy: Створена сторінка: The citation index was defined as the imply [https://www.medchemexpress.com/PF-670462.html PF-670462 site] quantity of citations per year. doi:10.1136/bmjopen-2...

The citation index was defined as the imply [https://www.medchemexpress.com/PF-670462.html PF-670462 site] quantity of citations per year. doi:10.1136/bmjopen-2016-Table 1 Bibliometric information associated with the top 20 of the top 100 cited articles [https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] in acute kidney injury Occasions cited (internet) 1971 Citation index (web) 164.25 Instances cited (Scopus) 2219 Citation index (Scopus) 184.Rank Authors 1 Bellomo et alTitle Acute renal failure: definition, outcome meas.Rigin. If there have been authors from numerous countries, the nation of origin was determined working with the country that the corresponding author belonged to. Those in the similar nation had been classified into those from 1 institute and those from a lot more than one institute. Articles that received funding source were identified. Degree of evidence for clinical studies was also identified, 2 and was evaluated based on the levels of evidence introductory document in the Oxford Centre for Evidence-based Medicine.19 In addition, journal name and IF have been also extracted. The journals IFs [https://dx.doi.org/10.3897/zookeys.482.8453 title= zookeys.482.8453] have been crossreferenced using the 2014 edition of Journal Citation Reports ( JCR): Science Edition (1945?014). Evaluating the included research Based on included study style, analysis setting and objectives, the selected articles were grouped into five categories: clinical recommendations, overview, meta-analysis, basic analysis and clinical investigation (which includes observational and randomised handle trials, RCTs). Prospective, retrospective and case series had been all categorised as observational studies. RCTs consist of both single-blind and double-blind research. Furthermore, as outlined by the causes of AKI, the subjects have been divided into (1) any bring about, (two) contrast, (3) cardiac surgery and (4) other people. Due to the fact some articles have been cited more often than others as a result of the distinction in time considering that publication, this error was adjusted by a citation index determined for each and every article. The citation index was defined as the mean variety of citations per year. For comparison, we searched Scopus (http://www. scopus.com/ search/form.url; retrieved on 15 July 2015) for total citation counts on the T100 [https://dx.doi.org/10.1080/00480169.2014.963792 title= 00480169.2014.963792] articles. Statistical evaluation Information are represented as median or IQR. The variations in between groups were evaluated by the Wilcoxon rank-sum test. The Spearman test was employed to evaluate the strength and path in the linear relationship among journal IF as well as the quantity of T100 cited articles or citations, as well as the correlation of short article citations among different databases (Net of Science Core Collection and Scopus). All information analyses had been performed with SPSS V.17 application (SPSS, Chicago, Illinois, USA). All probability values have been two-tailed, as well as the threshold for significance was set at p

Rigin. If there have been authors from many countries, the nation of

2017-12-09T10:44:38Z

Close25dinghy: Створена сторінка: The Spearman test was employed to evaluate the strength and path from the linear partnership between journal IF and also the number of T100 cited articles or ci...

The Spearman test was employed to evaluate the strength and path from the linear partnership between journal IF and also the number of T100 cited articles or citations, and the correlation of report citations involving distinctive databases (Net of Science Core Collection and Scopus). All information analyses had been performed with SPSS V.17 computer software (SPSS, Chicago, Illinois, USA). All probability values had been two-tailed, and also the threshold for significance was set at p[https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] in acute kidney injury Occasions cited (internet) 1971 Citation index (net) 164.25 Instances cited (Scopus) 2219 Citation index (Scopus) 184.Rank Authors 1 Bellomo et alTitle Acute renal failure: [http://hs21.cn/comment/html/?167596.html Ight be the case. Doctors who knowledge recurrent complaints may very well be] definition, outcome meas.Rigin. If there were authors from many countries, the country of origin was determined working with the country that the corresponding author belonged to. Those in the similar country had been classified into those from one institute and these from more than one particular institute. Articles that received funding supply were identified. Degree of evidence for clinical studies was also identified, two and was evaluated based around the levels of evidence introductory document in the Oxford Centre for Evidence-based Medicine.19 Moreover, journal name and IF were also extracted. The journals IFs [https://dx.doi.org/10.3897/zookeys.482.8453 title= zookeys.482.8453] had been crossreferenced with the 2014 edition of Journal Citation Reports ( JCR): Science Edition (1945?014). Evaluating the incorporated research Based on integrated study style, research setting and ambitions, the selected articles had been grouped into five categories: clinical suggestions, critique, meta-analysis, simple investigation and clinical research (including observational and randomised control trials, RCTs). Potential, retrospective and case series have been all categorised as observational research. RCTs include things like each single-blind and double-blind studies. Furthermore, in line with the causes of AKI, the topics had been divided into (1) any result in, (two) contrast, (three) cardiac surgery and (four) other individuals. Because some articles had been cited much more frequently than other individuals as a result of the difference in time considering that publication, this error was adjusted by a citation index determined for each and every article. The citation index was defined because the imply variety of citations per year. For comparison, we searched Scopus (http://www.

Ures, animal models, fluid therapy and data technologies needs: the Second

2017-12-09T10:28:37Z

Close25dinghy: Створена сторінка: Ures, animal models, fluid therapy and information technology requires: the Second International Consensus Conference in the Acute Dialysis Excellent Initiative...

Ures, animal models, fluid therapy and information technology requires: the Second International Consensus Conference in the Acute Dialysis Excellent Initiative (ADQI) Group Acute Kidney Injury Network: report of an initiative to enhance outcomes in acute kidney injury Acute renal failure in critically ill patients--a multinational, multicenter studyJournals [http://kfyst.com/comment/html/?250992.html Ion by Science and Technology (IWT Vlaanderen). DT is usually a Senior] Important CareYearsPMID 15 3122Mehta et al Uchino et alCritical Care JAMA--Journal on the American Medical Association New England Journal of Medicine Lancet20071652183.56 117.1725191.67 135.17 331 245 16 106Thadhani et al Mishra et alMedical progress--acute renal failure48.56.eight 618Chertow et alNeutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury just after cardiac surgery Acute kidney injury, mortality, length of stay, and charges in hospitalized patients Effects of diverse doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a potential randomised trial Oxygen no cost radicals in ischemic acute renal failure inside the rat Acute renal failure after coronary intervention: incidence, danger variables, and relationship to mortality The effect of acute renal failure on mortality--a [http://support.myyna.com/338586/toronto-ontario-canada-contributors-and-had-complete-access Toronto, Ontario, Canada Contributors GI and REM had full access to] cohort analysis86.98.15 811Ronco et alJournal with the American Society of Nephrology Lancet81.94.16 17751.64.ten 8928 9Paller et al McCullough et al Levy et alRihal et alSolomon et alIncidence and prognostic importance of acute renal failure right after percutaneous coronary intervention Effects of saline, mannitol, and furosemide [https://dx.doi.org/10.1016/j.toxlet.2015.11.022 title= j.toxlet.2015.11.022] to prevent acute decreases in renal function induced by radiocontrast agentsJournal of Clinical Investigation American Journal of Medicine JAMA--Journal with the American Health-related Association Circulation1984 1997814 79925.44 42.05 39.575 101617.97 53.47 49.six 434 591 9 375 704 eight 62249.62.12 010Open AccessNew England Journal of Medicine31.41.7 969ContinuedTable 1 Continued Instances cited (internet) [https://dx.doi.org/10.1371/journal.pone.0075009 title= journal.pone.0075009] 677 Citation index (internet) 56.42 Instances cited (Scopus) 844 Citation index (Scopus) 70.33 Rank Authors 13 Mehran et al Title A simple danger score for prediction of contrast-induced nephropathy soon after percutaneous coronary intervention--development and initial validation Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury Independent association involving acute renal failure and mortality following cardiac surgery Contrast material-induced renal failure in sufferers with diabetes mellitus, renal insufficiency, or each. A potential controlled study Nephrotoxic effects in high-risk patients undergoing angiography Acute renal failure in intensive care units--causes, outcome, and prognostic variables of hospital mortality: a prospective, multicenter study Administered mesenchymal stem cells protect against ischemic acute renal failure by way of differentiation-independent mechanisms Prevention of contrast-induced nephropathy with sodium bicarbonate--a randomized controlled trial Journals Journal on the American College of Cardiology Journal of your American Society of Nephrology American Journal of Medicine New England Journal of Medicine New England Journal of Medicine Important Care Medicine American Journal of Physiology-- Renal Physiology JAMA--Journal on the American Health-related Association Years 2004 PMID 15 464 318 [https://dx.doi.org/10.1140/epjc/s10052-015-3267-2 title= epjc/s10052-015-3267-2] 14 Mishra et al 2003 645 49.62 735 56.54 14 514 731 15Liu Y-hui, et al. BMJ Open 2016;6:e011630. doi:ten.1136/bmjopen-2016-Open AccessChertow et al Parfrey et al199863035.00 22.74741.five 23.9 576 407.Ures, animal models, fluid therapy and information and facts technology demands: the Second International Consensus Conference of the Acute Dialysis Good quality Initiative (ADQI) Group Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Acute renal failure in critically ill patients--a multinational, multicenter studyJournals Vital CareYearsPMID 15 3122Mehta et al Uchino et alCritical Care JAMA--Journal on the American Healthcare Association New England Journal of Medicine Lancet20071652183.56 117.1725191.67 135.17 331 245 16 106Thadhani et al Mishra et alMedical progress--acute renal failure48.56.8 618Chertow et alNeutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury following cardiac surgery Acute kidney injury, mortality, length of remain, and fees in hospitalized sufferers Effects of unique doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a potential randomised trial Oxygen no cost radicals in ischemic acute renal failure inside the rat Acute renal failure after coronary intervention: incidence, danger aspects, and connection to mortality The impact of acute renal failure on mortality--a cohort analysis86.98.15 811Ronco et alJournal of the American Society of Nephrology Lancet81.94.16 17751.64.ten 8928 9Paller et al McCullough et al Levy et alRihal et alSolomon et alIncidence and prognostic importance of acute renal failure immediately after percutaneous coronary intervention Effects of saline, mannitol, and furosemide [https://dx.doi.org/10.1016/j.toxlet.2015.11.022 title= j.toxlet.2015.11.022] to prevent acute decreases in renal function induced by radiocontrast agentsJournal of Clinical Investigation American Journal of Medicine JAMA--Journal with the American Health-related Association Circulation1984 1997814 79925.44 42.05 39.575 101617.97 53.47 49.6 434 591 9 375 704 8 62249.62.12 010Open AccessNew England Journal of Medicine31.41.7 969ContinuedTable 1 Continued Times cited (net) [https://dx.doi.org/10.1371/journal.pone.0075009 title= journal.pone.0075009] 677 Citation index (internet) 56.42 Instances cited (Scopus) 844 Citation index (Scopus) 70.33 Rank Authors 13 Mehran et al Title A basic threat score for prediction of contrast-induced nephropathy right after percutaneous coronary intervention--development and initial validation Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury Independent association in between acute renal failure and mortality following cardiac surgery Contrast material-induced renal failure in individuals with diabetes mellitus, renal insufficiency, or both.

Rigin. If there had been authors from multiple countries, the nation of

2017-12-09T07:24:35Z

Close25dinghy: Створена сторінка: Considering the fact that some articles had been cited more regularly than other individuals as a result of the [https://www.medchemexpress.com/PF-562271.html P...

Considering the fact that some articles had been cited more regularly than other individuals as a result of the [https://www.medchemexpress.com/PF-562271.html PF-562271 site] difference in time due to the fact publication, this error was adjusted by a citation index determined for every single write-up. doi:10.1136/bmjopen-2016-Table 1 Bibliometric information associated with the top 20 of the top 100 cited articles [https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] in acute kidney injury Instances cited (internet) 1971 Citation index (web) 164.25 Occasions cited (Scopus) 2219 Citation index (Scopus) 184.Rank Authors 1 Bellomo et alTitle Acute renal failure: definition, outcome meas.Rigin. If there had been authors from multiple countries, the nation of origin was determined applying the nation that the corresponding author belonged to. These in the very same country were classified into these from one particular institute and those from more than a single institute. Articles that received funding supply had been identified. Degree of proof for clinical research was also identified, two and was evaluated based on the levels of proof introductory document in the Oxford Centre for Evidence-based Medicine.19 Also, journal name and IF have been also extracted. The journals IFs [https://dx.doi.org/10.3897/zookeys.482.8453 title= zookeys.482.8453] had been crossreferenced with all the 2014 edition of Journal Citation Reports ( JCR): Science Edition (1945?014). Evaluating the included studies Primarily based on integrated study style, research setting and goals, the selected articles were grouped into five categories: clinical guidelines, critique, meta-analysis, basic analysis and clinical investigation (like observational and randomised control trials, RCTs). Prospective, retrospective and case series were all categorised as observational studies. RCTs incorporate each single-blind and double-blind research. Furthermore, according to the causes of AKI, the topics had been divided into (1) any cause, (2) contrast, (3) cardiac surgery and (four) others. Because some articles were cited additional frequently than other individuals as a result of the difference in time considering the fact that publication, this error was adjusted by a citation index determined for each short article. The citation index was defined as the imply number of citations per year. For comparison, we searched Scopus (http://www. scopus.com/ search/form.url; retrieved on 15 July 2015) for total citation counts from the T100 [https://dx.doi.org/10.1080/00480169.2014.963792 title= 00480169.2014.963792] articles. Statistical analysis Information are represented as median or IQR. The differences involving groups were evaluated by the Wilcoxon rank-sum test. The Spearman test was applied to evaluate the strength and path on the linear connection between journal IF and also the variety of T100 cited articles or citations, as well as the correlation of report citations in between different databases (Internet of Science Core Collection and Scopus). All information analyses were performed with SPSS V.17 computer software (SPSS, Chicago, Illinois, USA). All probability values have been two-tailed, plus the threshold for significance was set at p

Anges from five to 30?0 in sufferers beneath numerous conditions, for instance coronary

2017-12-08T00:55:36Z

Close25dinghy: Створена сторінка: Anges from five to 30?0 in sufferers under a variety of situations, such as coronary intervention,2 cardiac surgery3 and [http://europeantangsoodoalliance.com...

Anges from five to 30?0 in sufferers under a variety of situations, such as coronary intervention,2 cardiac surgery3 and [http://europeantangsoodoalliance.com/members/toad03spoon/activity/151607/ KI, followed by precise contrast-induced AKI (25 ) and cardiac surgery-induced AKI (15 ). Only] intensive care unit admission.four The improvement of AKI increases [http://support.myyna.com/335527/critiques-reported-statistically-important-improvements T (n=5). All electronic searches were performed on a single day, 15 July 2015, to avoid adjustments in citation rate as a great deal as you possibly can. Soon after all identified articles were retrieved, and also the final results have been sorted employing the choice `Times cited', which yielded a list of all the articles published in a specific journal ranked by citation number. The papers that had a larger citation density were ranked higher. Study choice Articles on the list were then reviewed by two independent reviewers (Y-hL and S-qW) by reading the abstracts acquired from Internet of Science. When it was necessary, the full texts were acquired from PubMed, EMBASE or ScienceDirect. Only research focusing on AKI as the key subject and in the English language were integrated. The exclusion nature12715 criteria were: (1) articles in languages other than English, (2) articles focused on other subjects other than about AKI. Any disagreement in between the two reviewers was resolved by way of discussion using a third reviewer ( J-hX).Anges from 5 to 30?0 in patients below numerous situations, such as coronary intervention,two cardiac surgery3 and intensive care unit admission.four The development of AKI increases hospital remain and healthcare costs, and leads to poor short-term and long-term outcomes.four Taking into consideration the value of AKI, researches within this field has been escalating, and several articles happen to be published annually, giving new insights in to the mechanism, early recognition and prevention or therapy of AKI.five six On the other hand, small is known relating to the high quality of scientific achievements within this location. Citation evaluation is a bibliometric course of action that determines the influence of an report inside the scientific community and evaluates the effect issue (IF) of a journal.7 The amount of citations received by an post is often a measure of its recognition and influence within the scientific community. A paper with higher citation history could be 2013/480630 additional useful in its field.eight 9 Furthermore, citation evaluation with the scientific literature may possibly help to recognize articles, study subjects andLiu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Open Access authors of influence.10 For that reason, academic institutions, funding agencies as well as the public come to be increasingly thinking about utilizing citation evaluation to assess the analysis good quality and productivity of individual researchers.7 Several attempts have already been made to determine essentially the most cited articles in numerous health-related disciplines, including psychology,11 radiology,12 hypospadiology,13 hypertension,14 surgery15 and cardiac surgery.16 However, no citation analysis of AKI has been s12687-015-0238-0 published to date. Therefore, we aimed to analyse the qualities with the one hundred top-cited articles focused on AKI, and to decide achievements and advances within this field throughout the previous century. Methods Search strategy We carried out a citation search in the Science Citation Index Expanded database with the Thomson Reuters Internet of Science Core Collection (Philadelphia, Pennsylvania, USA) from 1945 to 15 July 2015.]

Rigin. If there had been authors from many nations, the country of

2017-12-07T23:59:35Z

Close25dinghy: Створена сторінка: In addition, the number of citation and citations index per article were positivelyLiu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Liu Y-hui...

In addition, the number of citation and citations index per article were positivelyLiu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Liu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Table 1 Bibliometric information associated with the top 20 of the top 100 cited articles [https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] in acute kidney injury Instances cited (web) 1971 Citation index (web) 164.25 Times cited (Scopus) 2219 Citation index (Scopus) 184.Rank Authors 1 Bellomo et alTitle Acute renal failure: definition, outcome meas.Rigin. If there were authors from numerous nations, the country of origin was determined utilizing the nation that the corresponding author belonged to. Those from the exact same nation have been classified into those from a single institute and these from much more than a single institute. Articles that received funding source have been identified. Level of proof for clinical studies was also identified, 2 and was evaluated based around the levels of evidence introductory document in the Oxford Centre for Evidence-based Medicine.19 Additionally, journal name and IF had been also extracted. The journals IFs [https://dx.doi.org/10.3897/zookeys.482.8453 title= zookeys.482.8453] have been crossreferenced with all the 2014 edition of Journal Citation Reports ( JCR): Science Edition (1945?014). Evaluating the incorporated studies Based on integrated study style, investigation setting and objectives, the selected articles have been grouped into 5 categories: clinical recommendations, assessment, meta-analysis, standard research and clinical investigation (such as observational and randomised manage trials, RCTs). Prospective, retrospective and case series were all categorised as observational studies. RCTs include both single-blind and double-blind studies. Moreover, based on the causes of AKI, the topics had been divided into (1) any trigger, (2) contrast, (3) cardiac surgery and (four) other people. [https://www.medchemexpress.com/PF-4708671.html get PF-4708671] Considering the fact that some articles have been cited a lot more frequently than other individuals due to the difference in time considering that publication, this error was adjusted by a citation index determined for every single write-up. The citation index was defined as the mean number of citations per year. For comparison, we searched Scopus (http://www. scopus.com/ search/form.url; retrieved on 15 July 2015) for total citation counts with the T100 [https://dx.doi.org/10.1080/00480169.2014.963792 title= 00480169.2014.963792] articles. Statistical evaluation Data are represented as median or IQR. The variations between groups had been evaluated by the Wilcoxon rank-sum test. The Spearman test was used to evaluate the strength and direction on the linear partnership in between journal IF and also the quantity of T100 cited articles or citations, as well as the correlation of article citations amongst distinctive databases (Web of Science Core Collection and Scopus). All information analyses were performed with SPSS V.17 software program (SPSS, Chicago, Illinois, USA). All probability values had been two-tailed, plus the threshold for significance was set at p

Assumed that the distinction does not necessarily correspond to a moral

2017-12-06T12:19:38Z

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Similarly, the hormone oxytocin is usually produced artificially, exposing a nature-identical structure and knowledge ([24], 673?76).Authenticity Any individual? The Enhancement of [http://hsepeoplejobs.com/members/basketweeder69/activity/469743/ Nfluential basic investigation. Nonetheless, clinical research has bridged the gap amongst] feelings by way of Neuro-Psychopharmacologyartificial ones. His drug-based professions of appreciate cannot be take.Assumed that the distinction does not necessarily correspond to a moral distinction. Turning to the predicative aspect of artificiality, does the demarcation line prove clearer? Is there a thing just like the perceptible artificial top quality of an emotion? For authors including Achim Stephan [26], the answer is yes. In [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] a thought experiment, Stephan images a method to refer to what might be referred to as the qualitative artificiality of an emotion: A chemical laboratory creates substances that trigger totally [https://dx.doi.org/10.1128/AEM.01433-15 title= AEM.01433-15] novel emotional experiences, which is, emotions nobody has ever felt prior to. These new feelings, Stephan [26]: 311 claims, could rightly be calledHence, the intrinsic character of an artificial flavour could be named nature-identical. Correspondingly, there could be artificially developed feelings which might be nature-identical within the way the topic experiences them. Similarly, the hormone oxytocin might be created artificially, exposing a nature-identical structure and knowledge ([24], 673?76).Authenticity Any one? The Enhancement of Feelings through Neuro-Psychopharmacologyartificial ones. What he indicates by this really is that these feelings are artificial within a predicative sense. You will find fantastic reasons, on the other hand, to argue that artificiality isn't a felt good quality of an emotion. It appears not possible for an emotion to possess an artificial character as soon as it can be perceived. It can be important to note that the feelings persons on Prozac undergo are not experienced as artificial.6 They are artificial within the adverbial sense, but not artificial in [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] the predicative sense. In the first-person perspective, the artificially induced emotions under Prozac can't be distinguished from all-natural feelings. Patients on Prozac say they usually do not really feel drugged at all, but feel perfectly sober and clearheaded, whereas earlier antidepressants like tricyclics or MAOIs ordinarily created them really feel drugged ([9]: 66). On the other hand, the claim that feelings can't have an artificially felt character just isn't restricted to the effects of Prozac. Rather, I help the a lot more basic, conceptual thesis that individuals usually do not knowledge artificial emotions when taking drugs of what ever kind. It is absolutely not doable to feel the origin of an emotion after it can be perceived. Either someone has a specific feeling, or she or he doesn't have it. As soon as it is actually there, the person can no longer distinguish how it truly is brought about. Say an individual has offered Peter a drug that is definitely supposed to create him really feel proud, and say that the feelings produced by it differ qualitatively from his standard feelings of pride. Within this case, what Peter feels immediately after the intake of the drug is not artificial pride, but no pride at all. It should be a thing else, and also the utmost he can say is that what he feels may well resembleCf. Kass et al. [20]: p.

Anges from 5 to 30?0 in sufferers below different situations, including coronary

2017-12-06T10:23:35Z

Close25dinghy: Створена сторінка: Strategies [https://www.medchemexpress.com/Ponesimod.html ACT-128800 web] search approach We performed a citation search with the Science Citation Index Expande...

Strategies [https://www.medchemexpress.com/Ponesimod.html ACT-128800 web] search approach We performed a citation search with the Science Citation Index Expanded database of the Thomson Reuters Web of Science Core Collection (Philadelphia, Pennsylvania, USA) from 1945 to 15 July 2015. The following search crucial words had been applied: `acute kidney injury' or `AKI' or `acute renal failure' or `ARF'. All [https://www.medchemexpress.com/PKC412.html CGP41231] electronic searches were carried out on a single day, 15 July 2015, to avoid adjustments in citation rate as significantly as you can. Just after all identified articles have been retrieved, and also the outcomes were sorted utilizing the choice `Times cited', which yielded a list of all the articles published within a specific journal ranked by citation quantity. The papers that had a higher citation density have been ranked higher. Study selection Articles on the list were then reviewed by two independent reviewers (Y-hL and S-qW) by reading the abstracts acquired from Internet of Science. When it was essential, the complete texts had been acquired from PubMed, EMBASE or ScienceDirect. Only studies focusing on AKI as the major topic and in the English language had been incorporated. The exclusion [https://dx.doi.org/10.1038/nature12715 title= nature12715] criteria had been: (1) articles in languages apart from English, (2) articles focused on other subjects apart from about AKI. Any disagreement amongst the two reviewers was resolved through discussion with a third reviewer ( J-hX). Assessing the articles and journals Applying the modified approach of the methods by Lim et al17 and Azer and Azer,18 two reviewers (Y-hL and S-qW) reviewed the prime 100 cited (T100) articles and also the following data had been compiled: (1) citation number, (two) quantity of authors and authorship (initially, second and corresponding authors), (three) title, (four) publication year and (5) country of o.Anges from 5 to 30?0 in individuals beneath various circumstances, such as coronary intervention,two cardiac surgery3 and intensive care unit admission.4 The improvement of AKI increases hospital keep and healthcare expenses, and results in poor short-term and long-term outcomes.4 Considering the importance of AKI, researches within this field has been increasing, and several articles have been published annually, providing new insights in to the mechanism, early recognition and prevention or remedy of AKI.5 six On the other hand, small is identified regarding the top quality of scientific achievements within this location. Citation evaluation is really a bibliometric procedure that determines the influence of an report inside the scientific community and evaluates the effect issue (IF) of a journal.7 The number of citations received by an short article is actually a measure of its recognition and influence inside the scientific neighborhood. A paper with higher citation history may well be [https://dx.doi.org/10.1155/2013/480630 title= 2013/480630] much more beneficial in its field.8 9 Furthermore, citation analysis from the scientific literature may possibly support to recognize articles, analysis topics andLiu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Open Access authors of influence.ten For that reason, academic institutions, funding agencies as well as the public come to be increasingly enthusiastic about employing citation evaluation to assess the investigation top quality and productivity of person researchers.7 Many attempts have been created to recognize the most cited articles in several medical disciplines, which includes psychology,11 radiology,12 hypospadiology,13 hypertension,14 surgery15 and cardiac surgery.16 However, no citation analysis of AKI has been [https://dx.doi.org/10.1007/s12687-015-0238-0 title= s12687-015-0238-0] published to date.

Assumed that the distinction will not necessarily correspond to a moral

2017-12-05T02:36:34Z

Close25dinghy:

Similarly, the hormone oxytocin may be developed artificially, exposing a nature-identical structure and practical experience ([24], 673?76).Authenticity Any individual? The Enhancement of Emotions through Neuro-Psychopharmacologyartificial ones. What he implies by this really is that these feelings are artificial within a predicative sense. You'll find excellent reasons, nevertheless, to argue that artificiality is just not a felt high-quality of an emotion. It seems not possible for an emotion to have an artificial character when it is perceived. It really is significant to note that the feelings folks on Prozac undergo usually are not skilled as artificial.six They're artificial in the adverbial sense, but not artificial in [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] the predicative sense. In the first-person point of view, the artificially induced emotions beneath Prozac cannot be distinguished from all-natural feelings. Sufferers on Prozac say they do not feel drugged at all, but really feel perfectly sober and clearheaded, whereas earlier antidepressants which include tricyclics or MAOIs usually created them really feel drugged ([9]: 66). Nevertheless, the claim that emotions cannot have an artificially felt character will not be restricted for the effects of Prozac. Rather, I help the additional common, conceptual thesis that people don't experience artificial feelings when taking drugs of whatever type. It can be surely not attainable to feel the origin of an emotion when it's perceived. Either someone includes a particular feeling, or he or she will not have it. When it is actually there, the person can no longer distinguish how it can be brought about. Say an [http://www.entrespace.org/members/valueweeder12/activity/86215/ Ow, as an alternative to heavy breathing. So yes, that was that. (P] individual has offered Peter a drug that's supposed to produce him feel proud, and say that the feelings created by it differ qualitatively from his standard feelings of pride. In this case, what Peter feels immediately after the intake in the drug just isn't artificial pride, but no pride at all. It must be a thing else, along with the utmost he can say is the fact that what he feels could possibly resembleCf. Kass et al. [20]: p. 250 f.: A young man who, beneath the influence of Ecstasy, proposes to a young girl unknown to him, actually experiences his feelings of appreciate in that moment with out attributing an artificial top quality to it. As Kass et al. as proponents from the bio-conservatives place it: `Imagine that a young partygoer, below the influence of your drug, tells a young woman that he loves her and wants to marry her.Assumed that the distinction doesn't necessarily correspond to a moral distinction. Turning for the predicative aspect of artificiality, does the demarcation line prove clearer? Is there anything just like the perceptible artificial excellent of an emotion? For authors like Achim Stephan [26], the answer is yes. In [https://dx.doi.org/10.1016/j.susc.2015.06.022 title= j.susc.2015.06.022] a thought experiment, Stephan photos a way to refer to what may be referred to as the qualitative artificiality of an emotion: A chemical laboratory creates substances that trigger entirely [https://dx.doi.org/10.1128/AEM.01433-15 title= AEM.01433-15] novel emotional experiences, that is certainly, feelings no one has ever felt before. These new feelings, Stephan [26]: 311 claims, could rightly be calledHence, the intrinsic character of an artificial flavour is usually referred to as nature-identical.

2 643Aspelin et al44.58.12 571Brivet et al26.31.8 605Togel et al47.56.15 713Merten et

2017-12-02T16:25:36Z

Close25dinghy: Створена сторінка: Publishing journals of T100 articles The T100 articles were published in 30 journals (table 2), predominantly in general medical journals, led by the New Englan...

Publishing journals of T100 articles The T100 articles were published in 30 journals (table 2), predominantly in general medical journals, led by the New England Journal of Medicine (n=17), followed by expert medical journals, led by the Journal of the American Society of Nephrology (n=16) and Kidney International (n=16; table 2). In addition, Journal of Clinical Investigation, Lancet, Journal of the American Medical Association, American Journal [https://dx.doi.org/10.1155/2013/480630 title= 2013/480630] of Medicine and Crucial Care Medicine contributed 11, 7, five, 5 and five most cited articles, respectively. [https://dx.doi.org/10.1038/nature12715 title= nature12715] The journals IFs of T100 articles ranged from 2.1 to 55.9. A lot of of your T100 articles had been published within the high-IF journals, although the journal IF was drastically correlated together with the number of T100 articles (r=0.439, p=0.017), plus the number of citations (r=0.476, p=0.009). Authorship, origins and institutions The majority (83.7 ) of T100 articles were produced by teams involving 3 authors. A list with the most regularly appearing authors is presented in table 3. It's clearly dominated by JV Bonventre, who authored 10 T100 articles (initially author: 5; corresponding author: 9) with aFigure 1 Numbers of articles published and number of citations in 5-year periods.correlated in between the Net of Science and Scopus database (r=0.770, p[https://dx.doi.org/10.1098/rstb.2014.0252 title= rstb.2014.0252] factor 54.39 5.47 7.89 14.05 42.72 31.03 five.26 6.29 three.51 five.14 13.ten 14.ten five.29 17.47 ten.56 five.56 five.47 3.The journals that only published among the list of T100 articles had been shown under. Values provided in parentheses have been variety of articles, impact components as well as the corresponding citations, respectively. [http://minigamesuniverse.com/members/vinylyogurt89/activity/310070/ , a coding frame was created. If new codes emerged the coding] Circulation (1, 14.43, 6.

Anges from 5 to 30?0 in patients under numerous circumstances, for instance coronary

2017-12-02T14:47:38Z

Close25dinghy: Створена сторінка: Procedures Search tactic We performed a citation search of the Science Citation Index Expanded database of the Thomson Reuters Net of Science Core Collection (P...

Procedures Search tactic We performed a citation search of the Science Citation Index Expanded database of the Thomson Reuters Net of Science Core Collection (Philadelphia, Pennsylvania, USA) from 1945 to 15 July 2015. The following search important words were applied: `acute [https://www.medchemexpress.com/PF-4708671.html PF-4708671 custom synthesis] kidney injury' or `AKI' or `acute renal failure' or `ARF'. All electronic searches were performed on a single day, 15 July 2015, to prevent adjustments in citation price as a great deal as possible. Soon after all identified articles had been retrieved, plus the results have been sorted [https://www.medchemexpress.com/PHA-848125.html order Milciclib] making use of the selection `Times cited', which yielded a list of all the articles published inside a precise journal ranked by citation quantity. The papers that had a greater citation density were ranked greater. Study selection Articles on the list had been then reviewed by two independent reviewers (Y-hL and S-qW) by reading the abstracts acquired from Web of Science. When it was necessary, the full texts have been acquired from PubMed, EMBASE or ScienceDirect. Only studies focusing on AKI because the primary topic and within the English language were incorporated. The exclusion [https://dx.doi.org/10.1038/nature12715 title= nature12715] criteria were: (1) articles in languages besides English, (two) articles focused on other topics apart from about AKI. Any disagreement amongst the two reviewers was resolved through discussion with a third reviewer ( J-hX). Assessing the articles and journals Employing the modified strategy from the strategies by Lim et al17 and Azer and Azer,18 two reviewers (Y-hL and S-qW) reviewed the leading one hundred cited (T100) articles as well as the following information have been compiled: (1) citation number, (2) quantity of authors and authorship (first, second and corresponding authors), (3) title, (four) publication year and (5) country of o.Anges from 5 to 30?0 in patients below many situations, including coronary intervention,2 cardiac surgery3 and intensive care unit admission.4 The improvement of AKI increases hospital stay and healthcare costs, and results in poor short-term and long-term outcomes.4 Considering the significance of AKI, researches within this field has been rising, and several articles happen to be published annually, providing new insights into the mechanism, early recognition and prevention or remedy of AKI.5 six However, small is known concerning the high quality of scientific achievements within this area. Citation evaluation is actually a bibliometric method that determines the influence of an report within the scientific neighborhood and evaluates the impact aspect (IF) of a journal.7 The amount of citations received by an report is often a measure of its recognition and influence within the scientific community. A paper with higher citation history may well be [https://dx.doi.org/10.1155/2013/480630 title= 2013/480630] a lot more useful in its field.eight 9 Furthermore, citation evaluation in the scientific literature might aid to identify articles, study topics andLiu Y-hui, et al. BMJ Open 2016;6:e011630. doi:10.1136/bmjopen-2016-Open Access authors of influence.ten Consequently, academic institutions, funding agencies and also the public turn into increasingly thinking about making use of citation analysis to assess the analysis high quality and productivity of person researchers.7 A lot of attempts happen to be made to determine essentially the most cited articles in numerous healthcare disciplines, which includes psychology,11 radiology,12 hypospadiology,13 hypertension,14 surgery15 and cardiac surgery.16 Nonetheless, no citation analysis of AKI has been [https://dx.doi.org/10.1007/s12687-015-0238-0 title= s12687-015-0238-0] published to date.

91); Intensive Care Medicine (1, 7.21, 349); Nephrology Dialysis Transplantation (1, three.58, 304); Anesthesiology (1, 5.88, 263); Circulation Investigation (1, 11.02, 243); Journal of

2017-11-28T18:12:33Z

Close25dinghy: Створена сторінка: Articles originating from the USA also had the highest mean number of citations (mean 384 citations per article). Of the total T100 articles, the leading instit...

Articles originating from the USA also had the highest mean number of citations (mean 384 citations per article). Of the total T100 articles, the leading institutions with the most [https://dx.doi.org/10.1080/00480169.2014.963792 title= 00480169.2014.963792] productive articles were Brigham and Women's Hospital (Boston, Massachusetts, USA), [http://lisajobarr.com/members/active35spoon/activity/758033/ 91); Intensive Care Medicine (1, 7.21, 349); Nephrology Dialysis Transplantation (1, 3.58, 304); Anesthesiology (1, 5.88, 263); Circulation Research (1, 11.02, 243); Journal of] Cincinnati Children's Hospital Health-related Center (Cincinnati, Ohio, USA) and the University of California, San Francisco (San Francisco, California, USA), with 5 articles each. The institution ranking next will be the Yale University (West Haven, Connecticut, USA; table four).Figure 2 Nations of origin in the prime one hundred cited articles on acute kidney injury.Publication variety and regions of study The T100 articles included 69 clinical studies, 25 simple science research, 21 testimonials, 5 meta-analyses and 3 clinical suggestions (figure three). The number of total citations per write-up ranged from 218 to 1652 (median, 303) for clinical research, and from 215 to 814 (median, 257) for basic science. Of your 69 clinical articles, essentially the most frequent kind was prospective observational [http://betthelines.com/members/search08arch/activity/205981/ Specialty journals committed solely to study into renal ailments which include] studies (n=35), followed by RCTs (n=16), retrospective studies (n=16) and case reports (n=2). Additionally, 75 in the 16 RCTs have been published in the journals with high IF, eight in New England Journal of Medicine, 2 in Lancet and 2 in JAMA. Only 18 from the 51 observational research were published in journals with higher IF, and the majority of them (47 ) presented open access alternatives, and all of them were from potential observational studies, such as four in New England Journal of Medicine, two in Lancet and 3 in JAMA. Moreover, prospective observational studies had a larger median citation of per short article than the retrospective studies (median 298 vs 292). The principal purpose of those clinical studies integrated evaluation of a therapy approach (n=16), description of biomarkers or danger model to prevent AKI (n=9 and n=3, respectively), description of epidemiology (n=27), evaluation of a diagnostic modality (n=5) and other people (n=9). With regard towards the causes of AKI in clinical researches, most articles (55 ) integrated patients with any reason for A.91); Intensive Care Medicine (1, 7.21, 349); Nephrology Dialysis Transplantation (1, three.58, 304); Anesthesiology (1, 5.88, 263); Circulation Research (1, 11.02, 243); Journal of Thoracic and Cardiovascular Surgery (1, four.17, 229); International Journal of Molecular Medicine (1, two.09, 228); American Journal of Physiology (1, NA, 227); Clinical Infectious Ailments (1, 8.89, 226); Annals of Surgery (1, eight.33, 226); Annals of Thoracic Surgery (1, 3.85, 221); European Radiology (1, four.01, 220).Liu Y-hui, et al. BMJ Open 2016;6:e011630. doi:ten.1136/bmjopen-2016-Open AccessTable three Authors with two or more top-cited articles Rank 1 two 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Author Bonventre Devarajan Chertow Mehta Parikh Marenzi Schrier Camussi Dangas Kellum McCullough Schiffl Westenfelder Parfrey Bates Coca Number [https://dx.doi.org/10.1186/s12887-015-0481-x title= s12887-015-0481-x] of articles 10 eight 6 six 4 3 3 2 two 2 two two 2 2 two 2 Initial five 1 three 4 2 3 two 1 2 two 1 1 2 Correspond 9 5 5 3 4 3 three 2 2 2 two two 2 1 Other 1 3 1 1 Citations (initially and correspond) 4263 2464 2353 2757 996 813 1095 452 934 1788 1101 677 761 892 226 486 Total citations 4527 3428 2579 4728 813 1095 1634 452 934 1788 1101 677 761 892 [https://dx.doi.org/10.1371/journal.pone.0133807 title= journal.pone.0133807] 11191total of 4527 citations, and P Devarajan, who authored 8 T100 articles with 3428 citations.